The Evans Group


Queen's University

P. Andrew Evans
Group News



Queen's University

Chemistry Department

90 Bader Lane

Kingston, Ontario

K7L 3N6


Jadab Majhi has recently demonstrated the first Dynamic Kinetic Resolution of Tetrasubstituted Olefins.  A new concept in organic chemistry.  J. Am. Chem. Soc. 2019, 141, 30, 11770-11774

Queen’s University researcher P. Andrew Evans has uncovered a new process to deliver antibiotics using pollen to shield them.




Recent Publications
  "Copper-catalyzed desymmetrization of prochiral 4,4-disubstituted cyclopentenes via a site-selective allylic oxidation: a concise total synthesis of untenone A" Qingwen Gui, JuanJuan Wang, Sean Ng, Anja Dancevic, Timothy B Wright and P. Andrew Evans, ChemComm, 2019, 82
"Dynamic Kinetic Resolution of Alkenyl Cyanohydrins Derived from α,β-Unsaturated Aldehydes: Stereoselective Synthesis of E-Tetrasubstituted Olefins" Jadab Majhi, Ben W. H. Turnbull, Ho Ryu, Jiyong Park, Mu-Hyun Baik and P. Andrew Evans, J. Am. Chem., 2019, 141, 1770
Cover image  "Enantioselective Rhodium-Catalyzed Allylic Alkylation of β,γ-Unsaturated α-Amino Nitriles: Synthetic Homenolate Equivalents" Tim B. Wright, Ben. W. H. Turnbull and P. Andrew Evans, Angew. Chem. Int. Ed., 2019, 58, 9886
  "Asymmetric Rhodium-Catalyzed Allylic Substitution Reactions: Discovery, Development and Applications to Target-Directed Synthesis" Ben. W. H. Turnbull and P. Andrew Evans, J. Org.Chem., 2018, 83, 11463

"(11bS)-4-Methoxydinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine, [(S)-BINOL-POMe] and (11bR)-4-Methoxydinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine, [(R)-BINOL-POMe” Timothy B. Wright and P. Andrew Evans, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2018, 1-5.


"Rhodium-catalyzed [(3+2)+1] carbocyclization of alkynylidenecyclopropanes with carbon monoxide: construction of polysubstituted bicyclohexa-2,5-dienones” Andrew J. Burnie and P. Andrew Evans, Chem. Commun. 201854, 7621.

  “Intramolecular Thioether Migration in the Rhodium-Catalyzed Ene-Cycloisomerization of Alkenylidenecyclopropanes by a Metal-Mediates β-Sulfide Elimination", Yu, Su, P.A. Inglesby, P. Andrew Evans, Angew. Chem. Int. Ed., 2018, 57, 673.

“Regio- and Stereospecific Rhodium-Catalyzed Allylic Alkylation with an Acyl Anion Equivalent: An Approach to Acyclic alpha-Ternary-beta, gamma-Unsaturated Aryl Ketones" Ben W. H. Turnbull, Jungha Chae, Samuel Oliver, P. Andrew Evans, Chem. Sci. 2017, 8, 4001.